RERG protein (His tag) (80R-1679)
Purified recombinant Human RERG protein
|Synonyms||Ras-related and estrogen-regulated growth inhibitor protein, MGC15754|
Coomassie Blue stained SDS-PAGE of RERG protein (His tag) (80R-1679)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-199 amino acids: MGSSHHHHHH SSGLVPRGSH MAKSAEVKLA IFGRAGVGKS ALVVRFLTKR FIWEYDPTLE STYRHQATID DEVVSMEILD TAGQEDTIQR EGHMRWGEGF VLVYDITDRG SFEEVLPLKN ILDEIKKPKN VTLILVGNKA DLDHSRQVST EEGEKLATEL ACAFYECSAC TGEGNITEIF YELCREVRRR RMVQGKTRRR SSTTHVKQAI NKMLTKISS|
|Grade & Purity||> 85% pure|
|Molecular Weight||24.7 kDa (219aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 0.2M NaCl, 5mM DTT and 50% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||RERG is a 199 amino acid protein that localizes in the cytoplasm and belongs to the Ras subfamily of small GTPases. RERG is expressed in pancreas, liver, skin, lung, brain, kidney and heart tissue. It is a critical mediator of diverse cell signaling pathways, including those leading to cell proliferation, cytoskeletal organization and secretion. Recombinant human RERG protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.|
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