Retinoblastoma antibody detects endogenous levels of Retinoblastoma only when phosphorylated at threonine 826
Cross Reactivity
Mouse, Rat
Applications
ELISA, IF, WB
Immunogen
Retinoblastoma antibody was raised in Rabbit using synthesized phosphopeptide derived from human Retinoblastoma around the phosphorylation site of threonine 826 (K-M-TP-P-R) as the immunogen
Aliquot and store at -20 deg C. Avoid repeated freeze thaw cycles
General Information
Biological Significance
Should an oncogenic protein, such as those produced by cells infected by high-risk types of human papillomaviruses, bind and inactivate Retinoblastoma protein, this can lead to cancer.