RFXAP antibody (10R-1228)

Mouse monoclonal RFXAP antibody

Synonyms Monoclonal RFXAP antibody, Anti-RFXAP antibody, Anti RFXAP antibody, Regulatory factor X-associated protein antibody, Regulatory factor X-associated protein antibody, RFXAP antibody
Specificity Human RFXAP
Cross Reactivity Human, Mouse. Other species not studied
Applications Dot Blot, ELISA, WB
Immunogen RFXAP antibody was raised in mouse using recombinant Regulatory Factor X-Associated Protein (Rfxap)

Images

Western Blot analysis of immunized recombinant protein using RFXAP antibody (10R-1228)

Specifications

Host Mouse
Clone RFXAD55A
Isotype IgG1
Method of Purification RFXAP antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Form & Buffer RFXAP antibody in PBS (3.0 mM KCl, 1.5 mM KH2PO4 , 140 mM NaCl, 8.0 mM Na2HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3).
Concentration 100 ug/ml

Usage & Assay Information

Usage Recommendations WB: 0.2-2 ug/ml

Storage & Safety

Storage Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing.
Biohazard Information This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv

General Information

Biological Significance Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated ankyrincontaining protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group D. Transcript variants utilizing different polyA signals have been found for this gene.

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Images

  • Western Blot analysis of immunized recombinant protein using RFXAP antibody (10R-1228)

Availability: In stock

Price: €364.83
Size: 100 ug
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