RGS16 protein (His tag) (80R-1270)
Purified recombinant Human RGS16 protein
|Synonyms||RGS 16 protein, Regulator of G protein signaling 16 protein, RGS-R protein, Rgs14 protein, Regulator of G-protein signaling 16 A28 RGS14 protein, RGS-16 protein, A28-RGS14P protein, HGNC:9997 protein, RGS 16, RGS16, Retinally abundant regulator of G protein signaling protein, RGSR., A28-RGS14 protein, RGS 16 RGS R protein, A28 RGS14P protein, RGS-16|
Coomassie Blue stained SDS-PAGE of RGS16 protein (His tag) (80R-1270)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-202 amino acids: MGSSHHHHHH SSGLVPRGSH MCRTLAAFPT TCLERAKEFK TRLGIFLHKS ELGCDTGSTG KFEWGSKHSK ENRNFSEDVL GWRESFDLLL SSKNGVAAFH AFLKTEFSEE NLEFWLACEE FKKIRSATKL ASRAHQIFEE FICSEAPKEV NIDHETRELT RMNLQTATAT CFDAAQGKTR TLMEKDSYPR FLKSPAYRDL AAQASAASAT LSSCSLDEPS HT|
|Grade & Purity||> 90% pure|
|Molecular Weight||24.9 kDa (222aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in PBS, pH 7.4, containing 20% glycerol and 0.1M NaCl.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||RGS16, also known as regulator of G-protein signaling 16, belongs to 'regulator of G protein signaling' family and negatively regulates G protein coupled receptor signalling. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP bound form. It also may play a role in regulating the kinetics of signaling in the phototransduction cascade. Recombinant RGS16 protein was expressed in E. coli and purified by using conventional chromatography techniques.|
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