Rotavirus VP6 antibody (10-1020)
Mouse monoclonal Rotavirus VP6 antibody
Overview
Overview
| Synonyms | Monoclonal Rotavirus VP6 antibody, Anti-Rotavirus VP6 antibody, Rotavirus VP-6, Rotavirus VP 6, Rotavirus VP-6 antibody, VP6 antibody, Rotavirus VP 6 antibody, Rotavirus VP6 |
|---|---|
| Specificity | Reactive to VP6 protein of Rotavirus |
| Applications | ELISA |
| Immunogen | Rotavirus VP6 antibody was raised in mouse using Recombinant protein of Rotavirus VP6 (E.coli.) as the immunogen. |
| Assay Information | Matched pairs: The minimum detection limit on a sandwich ELISA using the capture antibody 10-1020 and the detector antibody 10-1022 is approximately 1 ng/mL of recombinant VP6 protein. |
Specifications
| Host | Mouse |
|---|---|
| Clone | M120536 |
| Isotype | IgG2a |
| Grade & Purity | > 95% pure |
| Method of Purification | Rotavirus VP6 antibody was purified by Protein A or G affinity purification |
| Form & Buffer | Supplied as a liquid in PBS, pH 7.4, 3mM KCl, 1.5mM KH2PO4, 140mM NaCl, 8.0mM Na2HPO4 |
| Concentration | 1-3 mg/ml |
Storage & Safety
| Storage | Store at 4 deg C for short term or -20 deg C for longer storage. Avoid repeated freeze/thaw cycles. |
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| Biohazard Information | This product contains sodium azide as a preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling. |
General Information
| Biological Significance | Rotavirus is the most common cause of severe diarrhoea among infants and young children. It is a genus of double-stranded RNA virus in the family Reoviridae. By the age of five, nearly every child in the world has been infected with rotavirus at least once. However, with each infection, immunity develops, and subsequent infections are less severe; adults are rarely affected. There are five species of this virus, referred to as A, B, C, D, and E. Rotavirus A, the most common, causes more than 90% of infections in humans. The virus is transmitted by the faecal-oral route. It infects and damages the cells that line the small intestine and causes gastroenteritis (which is often called "stomach flu" despite having no relation to influenza). There are six viral proteins (VPs) that form the virus particle (virion). These structural proteins are called VP1, VP2, VP3, VP4, VP6 and VP7. In addition to the VPs, there are six nonstructural proteins (NSPs), that are only produced in cells infected by rotavirus. These are called NSP1, NSP2, NSP3, NSP4, NSP5 and NSP6. |
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Rotavirus VP6 antibody
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