RPA14 antibody (70R-12487)

Affinity purified Rabbit polyclonal RPA14 antibody

Synonyms Polyclonal RPA14 antibody, Anti-RPA14 antibody, REPA3 antibody, RPA 14 antibody, RPA-14, replication protein A 14 kDa subunit antibody, RPA14, replication factor A protein 3 antibody, RPA3 antibody, RF-A protein 3 antibody, RP-A p14 antibody, RPA-14 antibody, RPA 14
Cross Reactivity Human
Applications IHC-P, WB
Immunogen RPA14 antibody was raised in rabbit using a recombinant fragment corresponding to a region within amino acids 1 and 121 of RPA14

Images

Immunohistochemical staining using RPA14 antibody (70R-12487)

Immunohistochemical staining of paraffin-embedded lung CA patient tumor using RPA14 antibody at a dilution of 1:100

Specifications

Host Rabbit
Isotype IgG
Method of Purification RPA14 antibody was purified by antigen-affinity chromatography
Molecular Weight 14 kDa
Form & Buffer Supplied as a concentrated soloution containing 1X PBS, 1% BSA, 20% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations IHC-P: 1:100-1:250, WB: 1:500-1:3000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions. Functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair; it does not support chromosomal DNA replication and cell cycle progression through S-phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.

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Images

  • <div><font face=Calibri size=2>Immunohistochemical staining using RPA14 antibody (70R-12487)</font></div>     | Immunohistochemical staining of paraffin-embedded lung CA patient tumor using RPA14 antibody at a dilution of 1:100
  • <div><font face=Calibri size=2>Western blot analysis using RPA14 antibody (70R-12487)</font></div>     | Western blot analysis of 30 ug of whole cell lysate (A:HeLa S3; B:Hep G2; C:MOLT4) using a 15 % SDS PAGE gel and RPA14 antibody at a dilution of 1:1000

Availability: In stock

Price: €395.09
Size: 100 ul
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