RRM1 antibody (70R-1598)

Rabbit polyclonal RRM1 antibody raised against the C terminal of RRM1

Synonyms Polyclonal RRM1 antibody, Anti-RRM1 antibody, R1 antibody, RRM 1 antibody, RRM 1, RR1 antibody, RIR1 antibody, RRM-1, RRM-1 antibody, RRM1, Ribonucleotide Reductase M1 Polypeptide antibody
Specificity RRM1 antibody was raised against the C terminal of RRM1
Cross Reactivity Human, Mouse, Rat, Dog
Applications WB
Immunogen RRM1 antibody was raised using the C terminal of RRM1 corresponding to a region with amino acids MHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEKLKDKEKVSKEEEEKER
Assay Information RRM1 Blocking Peptide, catalog no. 33R-6091, is also available for use as a blocking control in assays to test for specificity of this RRM1 antibody

Images

Western Blot analysis using RRM1 antibody (70R-1598)

RRM1 antibody (70R-1598) used at 1.25 ug/ml to detect target protein.

Specifications

Host Rabbit
Method of Purification Total IgG Protein A purified
Molecular Weight 90 kDa (MW of target protein)
Form & Buffer Lyophilized powder. Add 100ul distilled water for a 1mg/ml concentration of RRM1 antibody in PBS
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1.25 ug/ml

Storage & Safety

Storage Store at 2-8 deg C for short periods. For longer periods of storage, store at -20 deg C. Avoid repeat freeze-thaw cycles.

General Information

Biological Significance RRM1 is one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. Its gene is located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. Its gene may play a role in malignancies and disease that involve this region.

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Images

  • Western Blot analysis using RRM1 antibody (70R-1598) | RRM1 antibody (70R-1598) used at 1.25 ug/ml to detect target protein.

Availability: In stock

Price: €258.73
Size: 100 ug
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