Rubella virus protein (Grade 1) (30-1330)
Purified Native Rubella virus protein (Grade 1)
Overview
Overview
| Synonyms | Rubella protein, Rubella virus, Rubella K1S protein |
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| Species | Viral |
| Protein Type | Native |
| Applications | ELISA, Immunoassays, Lateral Flow |
Specifications
| Source | Strain HPV-77 cultured in Vero cells |
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| Grade & Purity | > 60% pure |
| Method of Purification | Supernatent is concentrated by crossflow ultrafiltration then purified by sucrose density gradient centrifugation |
| Form & Buffer | Supplied detergent freein NTE buffer (Sodium Chloride, TRIS and EDTA) |
| Concentration | 0.94 mg/ml |
Usage & Assay Information
| Usage Recommendations | Suitable for use in many IgG and IgM immunoassays |
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Storage & Safety
| Storage | Aliquot and store at -70 deg C to -100 deg C, avoid repeat freeze/thaw cycles |
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| Biohazard Information | Each lot of Rubella is inactivated using ultraviolet radtiation |
General Information
| Biological Significance | Rubella is transmitted by the respiratory route. The incubation period is 13 to 20 days, during which a viraemia occurs and virus disseminates throughout the body. In children the onset is abrupt with the appearance of the rash. In adults a prodromal phase may be present with fever and malaise for a day or two before the rash develops. The rash is typically a maculopapular rash, which first appears on the face and then spreads to the trunk and the limbs. The rash seldom lasts more than 3 days. The exact mechanism of how the rash is induced is uncertain but an immunopathological mechanism may be present. Lymphadenopathy may precede the rash by up to a week and persists up to 2 weeks after the rash has gone. |
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