S100A8 protein (30R-1524)
Purified recombinant Human S100A8 protein
|Synonyms||S 100, S100, Leukocyte L1 complex light chain protein, S 100 protein, BEE11 protein, CGLA protein, Neutrophil cytosolic 7 kDa protein protein, Migration inhibitory factor-related protein 8 protein, Calprotectin protein, S100 calcium binding protein A8 (calgranulin A) protein, S100A8 protein, Calprotectin L1L subunit protein, CP-10 protein, MA387 protein, p8 protein, CAGA protein, S-100 protein, Protein S100-A8 protein, Chemotactic cytokine CP-10 protein, NIF protein, MIF protein, AI323541 protein, L1Ag protein, S100A8/S100A9 complex protein, S100 calcium binding protein A8 60B8Ag protein, Calgranulin-A protein, MRP-8 protein, CFAG protein, Myeloid-related protein 8 protein, Cystic fibrosisprotein protein, B8Ag protein, Pro-inflammatory S100 cytokine protein, S-100, included protein, included protein, CAGA protein, Urinary stone protein band A.|
Coomassie Blue stained SDS-PAGE of S100A8 protein (30R-1524)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-93 amino acids: MLTELEKALN SIIDVYHKYS LIKGNFHAVY RDDLKKLLET ECPQYIRKKG ADVWFKELDI NTDGAVNFQE FLILVIKMGV AAHKKSHEES HKE|
|Grade & Purity||> 90% pure|
|Molecular Weight||10.8 Da (93aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 1mM DTT, and 10% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||S100 calcium binding protein A8, also known as MRP8, is a member of the S100 family, EF-hand superfamily of Calcium binding proteins. S100A8 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. It functions both intracellularly and extracellularly, where it binds to RAGE and CD36. Altered expression of this protein is associated with the disease cystic fibrosis. Recombinant human S100A8 was expressed in E. coli and purified by using conventional chromatography techniques.|
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