S100A8 protein (His tag) (80R-1841)
Purified recombinant S100A8 protein
|Synonyms||SA8-100, SA8-100 protein, S100A8, p8 protein, Caga protein, SA8 100 protein, Protein S100-A8 protein, AI323541 protein, MRP8 protein, B8Ag protein, CFAg protein, CP-10 protein, SA8 100, 60B8Ag protein|
Coomassie Blue stained SDS-PAGE of S100A8 protein (His tag) (80R-1841)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-89 amino acids: MGSSHHHHHH SSGLVPRGSH MPSELEKALS NLIDVYHNYS NIQGNHHALY KNDFKKMVTT ECPQFVQNIN IENLFRELDI NSDNAINFEE FLAMVIKVGV ASHKDSHKE|
|Grade & Purity||> 95% pure|
|Molecular Weight||12.4 kDa (109aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 30% glycerol, 0.1M NaCl and 1mM DTT.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||S100A8, also known MRP8, is a member of the S100 family, EF-hand superfamily of calcium binding proteins. This protein is localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. It functions both intracellularly and extracellularly, where it binds to RAGE and CD36. Altered expression of this protein is associated with the disease cystic fibrosis. Recombinant mouse S100A8 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.|
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