Polyclonal SCMH1 antibody, Anti-SCMH1 antibody, Scml3 antibody, SCMH-1, sex comb on midleg homolog 1 (Drosophila) antibody, SCMH 1 antibody, SCMH1, SCMH 1, SCMH-1 antibody, polycomb protein SCMH1 antibody, SCMH1 antibody
Cross Reactivity
Human
Applications
ICC, IF, IHC-P, WB
Immunogen
SCMH1 antibody was raised in rabbit using a recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 198 of SCMH1
Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
General Information
Biological Significance
Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.