Representing approximately 75% of serum immunoglobulins in humans, IgG or Immunoglobulin G is a common antibody isotype. It is a protein composed of four peptide chains, two identical heavy chains and two identical light chains arranged in the typical Y-shaped configuration of antibody monomers. Each IgG has two antigen binding sites.
IgG binds to many kinds of pathogens including viruses, bacteria, and fungi, and protects against them by the classic pathway of complement activation, opsonization for phagocytosis as well as neutralisation of their toxins. There are 4 subclasses in varying concentrations: IgG1 (66%), IgG2 (23%), IgG3 (7%) and IgG4 (4%). IgG is the only antibody that can protect a fetus by passing through the mother's placenta.
Fitzgerald Industries offers a vast range of IgG antibodies raised in all commonly used host animals and specific for Mouse, Goat, Rabbit, Human and others. Our IgG antibodies and IgG subclasses are of the highest quality and available in conjugated form to tags such as Fluorescein (FITC), biotin, horseradish peroxidase (HRP), PE and many more.
Our most popular IgG antibodies are:
Goat anti Rabbit IgG which is perfect for Immunoassays, Western blotting, Immunohistochemistry and purification applications.
Goat anti Human IgG is specific for Human IgG Fc region and can be used in Latex Immunoturbidimetric Assays and Nephelometric Assays.
Rabbit anti Mouse IgG1 is an excellent secondary antibody as it purified for greater specificity and can be applied to a range of applications including ELISA, IHC and Western blotting.
This conjugated Mouse anti Rat IgG1 (HRP) antibody is a monoclonal secondary antibody and can be used in ELISA and WB.
Visit our homepage and search for your favourite of IgG antibody!