Serum amyloid A protein (His tag) (80R-1189)

Purified recombinant Human Serum amyloid A protein

Synonyms PIG4 protein, MGC111216 protein, SAA protein, Tumor protein p53 inducible protein 4., Amyloid fibril protein AA protein, Serum amyloid A1 isoform 2 protein, SAA1 protein, Serum amyloid A1 isoform 1 protein, SAA2 protein, TP53I4 protein, Serum amyloid A protein precursor protein, Amyloid protein A protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of Serum amyloid A protein (His tag) (80R-1189)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 19-122 amino acids: MGSSHHHHHH SSGLVPRGSH MRSFFSFLGE AFDGARDMWR AYSDMREANY IGSDKYFHAR GNYDAAKRGP GGVWAAEAIS DARENIQRFF GHGAEDSLAD QAANEWGRSG KDPNHFRPAG LPEKY
Expression System E.coli
Grade & Purity > 95% pure
Molecular Weight 13.9 kDa (125aa), confirmed by MALDI-TOF.
Tag/Conjugate His tag
Form & Buffer Supplied as a liquid in 20mM Tris buffer, pH 8.0, containing 10% glycerol.
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Serum amyloid A1(SAA1) protein is made primarily in the liver and circulates in low levels in the blood. This protein appears to play a role in the immune system. Levels of this protein increase in the blood and other tissues under conditions of inflammation. SAA1 may help repair damaged tissues, acts as an antibacterial agent, and signal the migration of germ-fighting cells to sites of infection. Elevated levels of SAA over time predispose secondary amyloidosis, extracellular accumulation of amyloid fibrils, derived from a circulating precursor, in various tissues and organs. The most common form of amyloidosis occurs secondary to chronic inflammatory disease, particularly rheumatoid arthritis. Recombinant Serum amyloid A protein was expressed in E. coli and purified by using conventional chromatography techniques.

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Images

  • Coomassie Blue stained SDS-PAGE of Serum amyloid  A protein (His tag) (80R-1189) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: €169.35
Size: 100 ug
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