SF3A1 antibody (70R-5001)

Rabbit polyclonal SF3A1 antibody raised against the N terminal of SF3A1

Synonyms Polyclonal SF3A1 antibody, Anti-SF3A1 antibody, PRPF21 antibody, PRP21 antibody, SFA1 3 antibody, SFA1-3 antibody, SF3A1, SF3A120 antibody, SFA1 3, SFA1-3, Splicing Factor 3A Subunit 1 120Kda antibody, SAP114 antibody
Specificity SF3A1 antibody was raised against the N terminal of SF3A1
Cross Reactivity Human,Mouse,Rat
Applications WB
Immunogen SF3A1 antibody was raised using the N terminal of SF3A1 corresponding to a region with amino acids QQTTQQQLPQKVQAQVIQETIVPKEPPPEFEFIADPPSISAFDLDVVKLT
Assay Information SF3A1 Blocking Peptide, catalog no. 33R-7702, is also available for use as a blocking control in assays to test for specificity of this SF3A1 antibody

Images

Western Blot analysis using SF3A1 antibody (70R-5001)

SF3A1 antibody (70R-5001) used at 0.25 ug/ml to detect target protein.

Specifications

Host Rabbit
Method of Purification Affinity purified
Molecular Weight 89 kDa (MW of target protein)
Form & Buffer Lyophilized powder. Add 50ul distilled water for a 1mg/ml concentration of SF3A1 antibody in PBS
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 0.25 ug/ml

Storage & Safety

Storage Store at 2-8 deg C for short periods. For longer periods of storage, store at -20 deg C. Avoid repeat freeze-thaw cycles.

General Information

Biological Significance SF3A1 is the subunit 1 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 1 belongs to the SURP protein family; named for the SURP motifs that are thought to mediate RNA binding. Subunit 1 has tandemly repeated SURP motifs in its amino-terminal half while its carboxy-terminal half contains a proline-rich region and a ubiquitin-like domain. Binding studies with truncated subunit 1 derivatives demonstrated that the two SURP motifs are necessary for binding to subunit 3 while contacts with subunit 2 may occur through sequences carboxy-terminal to the SURP motifs.

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Images

  • Western Blot analysis using SF3A1 antibody (70R-5001) | SF3A1 antibody (70R-5001) used at 0.25 ug/ml to detect target protein.

Availability: In stock

Price: €285.10
Size: 50 ug
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