SGCD protein (His tag) (80R-2684)

Purified recombinant SGCD protein (His tag)

Synonyms Delta-sarcoglycan protein, 35DAG protein, CMD1L protein, DAGD protein, SG-delta protein, SGCDP protein, SGD protein, SGCD
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

SDS-PAGE analysis of SGCD protein (His tag) (80R-2684)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 57-289 aa: MGSSHHHHHH SSGLVPRGSH RSHMKVMNFT IDGMGNLRIT EKGLKLEGDS EFLQPLYAKE IQSRPGNALY FKSARNVTVN ILNDQTKVLT QLITGPKAVE AYGKKFEVKT VSGKLLFSAD NNEVVVGAER LRVLGAEGTV FPKSIETPNV RADPFKELRL ESPTRSLVME APKGVEINAE AGNMEATCRT ELRLESKDGE IKLDAAKIRL PRLPHGSYTP TGTRQKVFEI CVCANGRLFL SQAGAGSTCQ INTSVCL
Expression System E.coli
Grade & Purity > 85% pure
Molecular Weight 28 kDa
Tag/Conjugate His tag
Form & Buffer Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol
Concentration 1 mg/ml

Storage & Safety

Storage Can be stored at 4 deg C for short terms (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles

General Information

Biological Significance SGCD is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC). DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. The mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding distinct isoforms have been observed. In melanocytic cells SGCD gene expression may be regulated by MITF. Recombinant human SGCD protein, fused to His-tag at N-terminus, was expressed in E.coli.

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Images

  • <div><font face=Calibri size=2>SDS-PAGE analysis of SGCD protein (His tag) (80R-2684)</font></div>     | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: €223.13
Size: 100 ug
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