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SH3BP1 antibody (70R-13097)
Affinity purified Rabbit polyclonal SH3BP1 antibody
Synonyms
Polyclonal SH3BP1 antibody, Anti-SH3BP1 antibody, SH3 domain-binding protein 1 antibody, 3BP-1 antibody, SHBP1 3 antibody, SH3BP1, ARHGAP43 antibody, SH3BP1 antibody, SHBP1-3 antibody, SH3-domain binding protein 1 antibody, SHBP1-3, SHBP1 3, SH3 domain binding protein 1 antibody
Cross Reactivity
Human
Applications
ICC, IF, WB
Immunogen
SH3BP1 antibody was raised in rabbit using a synthetic peptide contain a sequence corresponding to a region within amino acids 639 and 651 of SH3BP1
Specifications
Host
Rabbit
Isotype
IgG
Method of Purification
SH3BP1 antibody was purified by antigen-affinity chromatography
Molecular Weight
76 kDa
Form & Buffer
Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Concentration
1 mg/ml
Usage & Assay Information
Usage Recommendations
IF:1:100-1:500, ICC:1:100-1:500, WB: 1:500-1:3000
Storage & Safety
Storage
Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
General Information
Biological Significance
Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho- or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac.
References
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Availability: In stock
Price:
€323.11
Size: 100 ul