SH3GLB2 protein (His tag) (80R-2592)
Purified recombinant SH3GLB2 protein
Overview
Overview
| Synonyms | SHGLB2 3, PP9455 protein, SHGLB2 3 protein, PP6569 protein, SHGLB2-3, Endophilin-B2 protein, SHGLB2-3 protein, SH3GLB2 |
|---|---|
| Species | Human |
| Protein Type | Recombinant |
| Applications | SDS-PAGE |
Images
SDS-PAGE analysis of SH3GLB2 protein (His tag) (80R-2592)
SDS-PAGE gel analysis of SH3GLB2 protein (His tag) where the figure is annotated with amount of protein run on the gel.
Specifications
| Residues | 1-395 aa: MGSSHHHHHH SSGLVPRGSH MGSMDFNMKK LASDAGIFFT RAVQFTEEKF GQAEKTELDA HFENLLARAD STKNWTEKIL RQTEVLLQPNPSARVEEFLY EKLDRKVPSR VTNGELLAQY MADAASELGP TTPYGKTLIK VAEAEKQLGA AERDFIHTAS ISFLTPLRNF LEGDWKTISK ERRLLQNRRL DLDACKARLK KAKAAEAKAT TVPDFQETRP RNYILSASAS ALWNDEVDKA EQELRVAQTE FDRQAEVTRL LLEGISSTHVNHLRCLHEFV KSQTTYYAQC YRHMLDLQKQ LGRFPGTFVG TTEPASPPLS STSPTTAAAT MPVVPSVASL APPGEASLCL EEVAPPASGT RKARVLYDYE AADSSELALL ADELITVYSL PGMDPDWLIG ERGNKKGKVP VTYLELLS |
|---|---|
| Expression System | E.coli |
| Grade & Purity | > 85% pure |
| Molecular Weight | 46.4 kDa |
| Tag/Conjugate | His tag |
| Form & Buffer | Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol,1mM DTT |
| Concentration | 0.5 mg/ml |
Storage & Safety
| Storage | Store at 4 deg C for short term storage, for long term storage aliquot and freeze at -20 deg C or -70 deg C |
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General Information
| Biological Significance | Endophilin-B2, also known as SH3GLB2, is a member of the endophilin B subgroup. The endophilins comprise a family of proteins that associate with amphiphysin, synaptojanin and dynamin and are implicated in presynaptic vesicle trafficking at nerve terminals. The expression patterns of the endophilins are consistent with their cellular functions at the neuronal synapse. SH3GLB2 is ubiquitously expressed but shows highest levels in brain, adult lung, ovary, and spinal cord. A decreased level of SH3GLB2 is found in Down syndrome and may reflect brain dysgenesis. |
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