Sheep anti Human IgG gamma (20C-CR6050SP)
Sheep anti Human IgG gamma antibody
Overview
Overview
| Synonyms | Polyclonal Human IgG gamma antibody, Anti-Human IgG gamma antibody |
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| Specificity | Human |
| Cross Reactivity | To be determined by end-user |
| Applications | Immunodiffusion, ODD, WB |
| Immunogen | Human IgG gamma antibody was raised in sheep using human IgG (Fc Fragment) as the immunogen. |
Specifications
| Host | Sheep |
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| Isotype | IgG |
| Form & Buffer | Supplied as a liquid in GBS. |
| Concentration | Batch dependent - please inquire should you have specific requirements |
Usage & Assay Information
| Usage Recommendations | ODD: 10 uL antiserum vs 5 uL Serum, WB: 100 uL antiserum vs 5 uL Serum, Immunodiffusion: 2 uL antiserum/cm^2 in gel vs 5 uL Serum, dilutions: 1:5 - 1:50. |
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Storage & Safety
| Storage | Store at 4 deg C. |
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General Information
| Biological Significance | IgG is the most abundant immunoglobulin in plasma, found at a concentration of 8 to 18 mg/ml. This immunoglobulin plays a very important role in the defense against infection for newborns because of its transfer through the placenta during pregnancy. It readily diffuses into the extravascular body spaces where it plays a major role in neutralizing bacterial toxins and in enhancing the phagocytosis of microorganisms. IgG binds to bacteria and these complexes adhere to phagocytic cells which have surface receptors specific for IgG. |
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