Sheep anti Human IgM (40C-CR2023S)
Sheep anti Human IgM antibody
Overview
Overview
| Synonyms | Polyclonal Human IgM antibody, Anti-Human IgM antibody |
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| Specificity | Human |
| Cross Reactivity | To be determined by end-user |
| Applications | Immunodiffusion, ODD, WB |
| Immunogen | Human IgM antibody was raised in sheep using human IgM (Fc Fragment) as the immunogen. |
Specifications
| Host | Sheep |
|---|---|
| Isotype | IgM |
| Form & Buffer | Supplied as neat serum with 0.1% NaN3 add as a preservative. |
Usage & Assay Information
| Usage Recommendations | ODD: 10 uL antiserum vs 10 uL Serum, WB: 100 uL antiserum vs 10 uL Serum, Immunodiffusion: 0.375 uL antiserum/cm^2 in gel vs 5 uL Serum, dilutions: Neat - 1:10. |
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Storage & Safety
| Storage | Store at 4 deg C. |
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General Information
| Biological Significance | IgM is found in normal plasma at a concentration of 1.2 to 4.0 mg/ml. It is the first immunoglobulin produced during the immune response, the first antibody in neonates, and is involved in pathogenesis of autoimmune diseases. A diminished level of IgM is associated with Wiskott-Aldrich syndrome. |
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