SHH antibody (70R-13756)

Affinity purified Rabbit polyclonal SHH antibody

Synonyms Polyclonal SHH antibody, Anti-SHH antibody, SMMCI antibody, TPTPS antibody, Sonic Hedgehog antibody, TPT antibody, Sonic Hedgehog Homolog antibody, HLP3 antibody, HHG1 antibody, HPE3 antibody
Applications IHC-P, WB
Immunogen SHH antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the N-terminal of human SHH, identical to the related Rabbit and rat sequences, as the immunogen

Images

Immunohistochemical staining using SHH antibody (70R-13756)

Immunohistochemistry of paraffin-embedded section of Rat Brain Tissue

Specifications

Host Rabbit
Isotype IgG
Method of Purification SHH antibody was purified by affinity chromatography
Form & Buffer Supplied in lyophilized form

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles.

General Information

Biological Significance SHH is a protein that is instrumental in patterning the early embryo. It has been implicated as the key inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites. Defects in this protein or in its signalling pathway are a cause of holoprosencephaly (HPE). It is also thought that mutations in its gene or in its signalling pathway may be responsible for VACTERL syndrome, which is characterized by vertebral defects, anal atresia, tracheoesophageal fistula with esophageal atresia, radial and renal dysplasia, cardiac anomalies, and limb abnormalities.

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Images

  • <div><font face=Calibri size=2>Immunohistochemical staining using SHH antibody (70R-13756)</font></div>     | Immunohistochemistry of paraffin-embedded section of Rat Brain Tissue

Availability: In stock

Price: €269.12
Size: 100 ug
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