SIV mac251 p28 antibody (HRP) (61-002202)
Mouse monoclonal SIV mac251 gp120 antibody (HRP)
Overview
Overview
| Synonyms | Monoclonal SIV mac251 gp28 antibody, Anti-SIV mac251 gp28 antibody, SIV mac25 p28 1, SU antibody, gp28 glycoprotein antibody, SIV mac25 p28-1, SIV mac25 p28-1 antibody, SIV1 mac251 p28, Surface protein antibody, SIV mac25 p28 1 antibody, gp28 antibody, Simian Immunodeficiency Virus 1 antibody, Glycoprotein 28 antibody, Envelope surface glycoprotein gp28 antibody, gp28 antibody |
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| Specificity | SIV1 mac251 p28 |
| Applications | ELISA, WB |
| Immunogen | SIV mac251 p28 antibody was raised in mouse using SIV mac251 p28 as the immunogen. |
| Assay Information | Binds to recombinant p28 (SIV mac251), not epitope mapped. |
Specifications
| Host | Mouse |
|---|---|
| Clone | 3F7 |
| Isotype | IgG1 |
| Tag/Conjugate | HRP |
| Form & Buffer | Supplied as a purified IgG in 50mM Tris buffer, pH 8.0, with no preservatives added. The HRP is attached by glutaraldehyde coupling to the lysine residue. |
| Concentration | 50 ug/vial |
Usage & Assay Information
| Usage Recommendations | ELISA: 1:1000, WB: 1:500-1:1000 |
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Storage & Safety
| Storage | Store lyophilized product at 2-8 deg C short term, following reconstitution, aliquot and store at -70 deg C or lower. Avoid repeated freeze/thaw cycles |
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| Biohazard Information | Not tested for sterility or endotoxin content. |
General Information
| Biological Significance | HIV1 is equipped with the envelope gp160 glycoprotein for interaction with Langerhans cells and dendritic cells, which confront the virus at the portal of virus entry in the human body. These cells are equipped with receptors by which they bind and endocytose the virus. The gp120 glycoprotein is used for binding to CD4 receptor and CCR5 co-receptor of T helper 2 (Th2) cells, and is able to induce FcepsilonRI(+) hematopoietic cells to produce IL4. This inactivates the host adaptive immune response. |
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