SIV mac251 p28 protein (HRP) (65-022002)
Purified recombinant SIV mac251 gp28 (HRP)
Overview
Overview
| Synonyms | Simian Immunodeficiency Virus 1, Surface protein, SIV mac251 p28, SIV mac251 gp28 biotin conjugate, Glycoprotein 28, SIV mac251 gp28 protein, Envelope surface glycoprotein 28, SU, SIV mac 251 p28, SIV mac 251 p28 protein, SIV mac-251 p28, SIV mac-251 p28 protein |
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| Species | Viral |
| Protein Type | Recombinant |
| Applications | ELISA, WB |
Specifications
| Expression System | E.coli |
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| Grade & Purity | > 90% pure |
| Tag/Conjugate | HRP |
Storage & Safety
| Storage | Store lyophilized product at 2-8 deg C short term, following reconstitution, aliquot and store at -70 deg C or lower. Avoid repeated freeze/thaw cycles |
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General Information
| Biological Significance | HIV1 is equipped with the envelope gp160 glycoprotein for interaction with Langerhans cells and dendritic cells, which confront the virus at the portal of virus entry in the human body. These cells are equipped with receptors by which they bind and endocytose the virus. The gp120 glycoprotein is used for binding to CD4 receptor and CCR5 co-receptor of T helper 2 (Th2) cells, and is able to induce FcepsilonRI(+) hematopoietic cells to produce IL4. This inactivates the host adaptive immune response. |
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