SKP1 protein (30R-1430)
Purified recombinant Human SKP1 protein
|Synonyms||SKP-1, MGC34403 protein, Transcription elongation factor B protein, p19A protein, S-phase kinase-associated protein 1 isoform a Cyclin A/CDK2 associated p19 protein, SKP-1 protein, Organ of Corti protein 2 protein, EMC19 protein, S phase kinase associated protein 1 protein, SKP1A protein, SKP 1A protein, SKP 1 protein, OCP-II protein, MGC34403 protein, RNA polymerase II elongation factor like protein OCP2 protein, TCEB1L protein, OCPII protein, RNA polymerase II elongation factor like protein protein, SIII protein, OCP 2 protein, p19skp1 protein, S phase kinase associated protein 1A p19A protein, Transcription elongation factor B SIII polypeptide 1 like., Transcription Elongation Factor B 1 like protein, OCP II protein, SKP1, Cyclin A/CDK2 associated protein p19 protein, Skp 1 protein, SKP 1, OCP2 protein, OCP II protein protein, S phase kinase associated protein 1A protein|
Coomassie Blue stained SDS-PAGE of SKP1 protein (30R-1430)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-160 amino acids: MPSIKLQSSD GEIFEVDVEI AKQSVTIKTM LEDLGMDDEG DDDPVPLPNV NAAILKKVIQ WCTHHKDDPP PPEDDENKEK RTDDIPVWDQ EFLKVDQGTL FELILAANYL DIKGLLDVTC KTVANMIKGK TPEEIRKTFN IKNDFTEEEE AQVGSTQFCL|
|Grade & Purity||> 90% pure|
|Molecular Weight||18 kDa (160aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 50mM NaCl, and 10% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||S-phase kinase-associated protein 1, also known as SKP1, is an F-box protein which functions as a substrate recognition component of the SCF ubiquitin ligase complex. It binds to proteins containing an F-box motif, such as cyclin F, S-phase kinase-associated protein 2, and other regulatory proteins involved in ubiquitin dependent proteolysis. It is also involved in the control of beta-catenin levels and the activity of beta-catenin dependent TCF transcription factors. Recombinant human SKP1 protein was expressed in E. coli and purified by using conventional chromatography techniques.|
Sorry, but there are no references currently for this product.
You need to be logged in to write a review. Please login here
Sorry there are currently no reviews for this product