SKP1 protein (30R-1430)

Purified recombinant Human SKP1 protein

Synonyms SKP-1, MGC34403 protein, Transcription elongation factor B protein, p19A protein, S-phase kinase-associated protein 1 isoform a Cyclin A/CDK2 associated p19 protein, SKP-1 protein, Organ of Corti protein 2 protein, EMC19 protein, S phase kinase associated protein 1 protein, SKP1A protein, SKP 1A protein, SKP 1 protein, OCP-II protein, MGC34403 protein, RNA polymerase II elongation factor like protein OCP2 protein, TCEB1L protein, OCPII protein, RNA polymerase II elongation factor like protein protein, SIII protein, OCP 2 protein, p19skp1 protein, S phase kinase associated protein 1A p19A protein, Transcription elongation factor B SIII polypeptide 1 like., Transcription Elongation Factor B 1 like protein, OCP II protein, SKP1, Cyclin A/CDK2 associated protein p19 protein, Skp 1 protein, SKP 1, OCP2 protein, OCP II protein protein, S phase kinase associated protein 1A protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of SKP1 protein (30R-1430)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-160 amino acids: MPSIKLQSSD GEIFEVDVEI AKQSVTIKTM LEDLGMDDEG DDDPVPLPNV NAAILKKVIQ WCTHHKDDPP PPEDDENKEK RTDDIPVWDQ EFLKVDQGTL FELILAANYL DIKGLLDVTC KTVANMIKGK TPEEIRKTFN IKNDFTEEEE AQVGSTQFCL
Expression System E.coli
Grade & Purity > 90% pure
Molecular Weight 18 kDa (160aa), confirmed by MALDI-TOF.
Form & Buffer Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 50mM NaCl, and 10% glycerol.
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance S-phase kinase-associated protein 1, also known as SKP1, is an F-box protein which functions as a substrate recognition component of the SCF ubiquitin ligase complex. It binds to proteins containing an F-box motif, such as cyclin F, S-phase kinase-associated protein 2, and other regulatory proteins involved in ubiquitin dependent proteolysis. It is also involved in the control of beta-catenin levels and the activity of beta-catenin dependent TCF transcription factors. Recombinant human SKP1 protein was expressed in E. coli and purified by using conventional chromatography techniques.

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Images

  • Coomassie Blue stained SDS-PAGE of SKP1 protein (30R-1430) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: €206.99
Size: 100 ug
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