SMC1A antibody (70R-13301)

Affinity purified Rabbit polyclonal SMC1A antibody

Synonyms Polyclonal SMC1A antibody, Anti-SMC1A antibody, SMC protein 1A antibody, SMCA 1 antibody, SMCA 1, CDLS2 antibody, SB1.8 antibody, SMCB antibody, SMC1L1 antibody, DXS423E antibody, KIAA0178 antibody, SMCA-1 antibody, SMCA-1, SMC1 structural maintenance of chromosomes 1-like 1 antibody, SMC1A, DKFZp686L19178 antibody, SMC-1A antibody, SMC1 antibody, MGC138332 antibody, SMC1alpha antibody, SMC1A antibody
Cross Reactivity Human
Applications IHC-P, WB

Images

Immunohistochemical staining using SMC1A antibody (70R-13301)

Immunohistochemical staining of paraffin-embedded A549 Xenograft using SMC1A antibody at a dilution of 1:100

Specifications

Host Rabbit
Isotype IgG
Method of Purification SMC1A antibody was purified by antigen-affinity chromatography
Molecular Weight 143 kDa
Form & Buffer Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations IHC-P: 1:100-1:500, WB: 1:1000-1:10000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes proteins, SMC3 and either SMC1L2 or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation.

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Images

  • <div><font face=Calibri size=2>Immunohistochemical staining using SMC1A antibody (70R-13301)</font></div>     | Immunohistochemical staining of paraffin-embedded A549 Xenograft using SMC1A antibody at a dilution of 1:100
  • <div><font face=Calibri size=2>Western blot analysis using SMC1A antibody (70R-13301)</font></div>     | Western blot analysis of 30 ug of whole cell lysate (A: Molt-4) using a 7.5 % SDS PAGE gel and SMC1A antibody at a dilution of 1:5000

Availability: In stock

Price: €323.11
Size: 100 ul
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