SMPD3 Blocking Peptide (33R-8099)
A synthetic peptide for use as a blocking control in assays to test for specificity of SMPD3 antibody, catalog no. 70R-7194
Overview
Overview
| Synonyms | SMPD3 control peptide, SMPD3 antibody Blocking Peptide, Anti-SMPD3 Blocking Peptide, Sphingomyelin Phosphodiesterase 3 Neutral Membrane Blocking Peptide, Neutral Sphingomyelinase Ii Blocking Peptide, FLJ22593 Blocking Peptide, MGC138443 Blocking Peptide, NSMASE2 Blocking Peptide, SMPD3, SMPD-3, SMPD 3, SMPD-3 Blocking Peptide, SMPD 3 Blocking Peptide |
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| Protein Type | Synthetic |
| Applications | IHC, WB |
Specifications
| Residues | RPPEADDPVPGGQARNGAGGGPRGQTPNHNQQDGDSGSLGSPSASRESLV |
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| Molecular Weight | 71 kDa |
| Form & Buffer | Lyophilized powder. Add 100ul of distilled water for a final peptide concentration is 1 mg/ml. |
Storage & Safety
| Storage | Store at -20 deg C long term. Avoid repeat freeze-thaw cycles. |
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General Information
| Biological Significance | SMPD3 catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. SMPD3 regulates the cell cycle by acting as a growth suppressor in confluent cells. It probably acts as a regulator of postnatal development and participates in bone and dentin mineralization. |
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