SNAP23 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the C-terminal of human SNAP23, different from the related rat and Rabbit sequencesby three amino acids as the immunogen
Immunohistochemical staining using SNAP23 antibody (70R-14311)
Immunohistochemistry of paraffin-embedded section of Human Placenta Tissue
SNAP23 antibody
Immunohistochemical staining using SNAP23 antibody (70R-14311)
Immunohistochemistry of paraffin-embedded section of Human Placenta Tissue
Western Blot analysis using SNAP23 antibody (70R-14311)
Lane 1:Human Placenta Tissue Lysate; Lane 2:Rat Testicle Tissue Lysate; Lane 3:Rat Spleen Tissue Lysate; Lane 4:Hela Cell Lysate; Lane 5:M453 Cell Lysate
Specifications
Host
Rabbit
Isotype
IgG
Method of Purification
SNAP23 antibody was purified by affinity chromatography
Optimal conditions to be determined by the end user
Storage & Safety
Storage
Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles.
General Information
Biological Significance
SNAP23 is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this genepecificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin.