snRNP A protein (30R-2124)

Purified recombinant snRNP A protein

Synonyms snRNP A, Small nuclear ribonucleoprotein A
Protein Type Recombinant
Applications User optimized

Specifications

Expression System HeLa cells
Molecular Weight 34 kDa
Form & Buffer Supplied in lyophilized form with 25 mM Tris, 190 mM glycine, 0.025% (w/v) SDS, pH 8.4
Concentration 0.1 mg/ml

Storage & Safety

Storage Store at 2-8 deg C in lyophilized form. Following reconstitution aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance snRNPs are RNA-protein complexes that combine with unmodified pre-mRNA and various other proteins to form a spliceosome, a large RNA-protein molecular complex upon which splicing of pre-mRNA occurs. The action of snRNPs is essential to the removal of introns from pre-mRNA, a critical aspect of post-transcriptional modification of RNA, occurring only in the nucleus of eukaryotic cells. The A protein is a target for anti-RNP sera. Autoimmune antibodiesagainst this protein are present in sera from patients with MCTD and with SLE

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Availability: In stock

Price: €317.38
Size: 20 ug
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