SSB La protein (30-AS74)
Purified native Bovine SSB La protein
Overview
Overview
| Synonyms | SSB protein, Single stranded binding protein, Single stranded binding La protein |
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| Species | Bovine |
| Protein Type | Native |
| Applications | ELISA |
Specifications
| Source | Calf Thymus |
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| Grade & Purity | > 90% pure |
| Molecular Weight | 48 kDa |
| Form & Buffer | 20mM Hepes-NaOH, pH 7.4, with 0.32M NaCl, 0.2mM dithiothreitol, 0.1mM PMSF, 20% glycerol, and stabilizers. |
| Concentration | Batch dependent - please inquire should you have specific requirements |
Usage & Assay Information
| Usage Recommendations | 0.5-1 ug/ml |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | La antigen binds to the oligo(U) 3' termini of nascent RNA polymerase III transcripts and facilitates transcriptional termination and reinitiation by this enzyme13,-17. It has also been reported to function as an ATP-dependent helicase able to melt RNA-DNA hybrids. |
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