SSX2 antibody (70R-13829)
Affinity purified Rabbit polyclonal SSX2 antibody
Overview
Overview
| Synonyms | Polyclonal SSX2 antibody, Anti-SSX2 antibody, SSX 2 antibody, SSX antibody, SSX-2 antibody, SSX-2, X breakpoint 2 antibody, SSX2, HD21 antibody, HOM-MEL-40 antibody, MGC15364 antibody, MGC119055 antibody, synovial sarcoma, MGC3884 antibody, SSX 2 |
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| Applications | IHC-P, WB |
| Immunogen | SSX2 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the C-terminal of human SSX2 as the immunogen |
Images
Western Blot analysis using SSX2 antibody (70R-13829)
Lane 1: MCF-7 Cell Lysate; Lane 2: Hela Cell Lysate
Specifications
| Host | Rabbit |
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| Isotype | IgG |
| Method of Purification | SSX2 antibody was purified by affinity chromatography |
| Form & Buffer | Supplied in lyophilized form |
Usage & Assay Information
| Usage Recommendations | Optimal conditions to be determined by the end user |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | SSX2 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene. |
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