Staphylococcus Enterotoxin Type I antibody (10-7828)

Mouse monoclonal Staphylococcus Enterotoxin I antibody

Synonyms Monoclonal Enterotoxin I Staphylococcus Aureus antibody, Anti-Enterotoxin I Staphylococcus Aureus antibody, Staphylococcus Aureus I antibody, Enterotoxin I Staphylococcus Aureus antibody, Enterotoxin I Staphylococcus Aureus antibody, Enterotoxin I Staphylococcus Aureus antibody, Staphylococcus Aureus I antibody, Anti Enterotoxin I Staphylococcus Aureus antibody
Specificity Staphylococcus Enterotoxin B
Applications ELISA, Immunoassays
Immunogen Staphylococcus Enterotoxin I antibody was raised in mouse using recombinant St. aureus enterotoxin I expressed in E. coli as the immunogen
Assay Information 10-7827 can be used in a sandwich immunoassay as a conjugate antibody in conjunction with 10-7828 as the coating antibody

Specifications

Host Mouse
Clone M18612EI2
Isotype IgG2a
Method of Purification Staphylococcus Enterotoxin I antibody was purified by chromatography on protein G Sepharose.
Form & Buffer Supplied in PBS, pH 7.4, 0.1 % NaN3.

Storage & Safety

Storage Store at 4 deg C

General Information

Biological Significance Heat-labile enterotoxin is a type of labile toxin found in Escherichia coli that is inactivated at high temperatures. It acts similarly to the cholera toxin by raising cAMP levels through ADP-ribosylation of the alpha-subunit of a Gs protein leading to the constitutive activation of adenylate cyclase. Elevated cAMP levels stimulate secretion of Chloride ions and water from the enterocyte into the gut lumen, thus causing watery diarrhea. In addition to its effects on chloride secretion, which involve the same steps as the effects of cholera toxin, heat-labile enterotoxin binds additional substrates: lipopolysaccharide on the surface of E. coli cells and A-type blood antigens. The importance of these binding events is not yet known.

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Staphylococcus Enterotoxin Type I antibody

Mouse monoclonal Staphylococcus Enterotoxin I antibody

Availability: In stock

Price: €257.67
Size: 1 mg
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