STIM1 protein (Calmodulin tag) (80R-1062)

Purified recombinant Human STIM1 protein (Calmodulin tag)

Synonyms STIM 1, SIM protein, Stromal interaction molecule 1 protein, STIM1 protein, D11S4896E protein, STIM 1 protein, GOK protein, Stromal interaction molecule 1 D11S4896E protein, STIM-1, STIM 1 protein, STIM1, Stim1 stromal interaction molecule 1., STIM-1 protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of STIM1 protein (Calmodulin tag) (80R-1062)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 23-213 amino acids: MADQLTEEQI AEFKEAFSLF DKDGDGTITT KELGTVMRSL GQNPTEAELQ DMINEVDADG NGTIDFPEFL TMMARKMKDT DSEEEIREAF RVFDKDGNGY ISAAELRHVM TNLGEKLTDE EVDEMIREAD IDGDGQVNYE EFVQMMTAKG SMLSHSHSEK ATGTSSGANS EESTAAEFCR IDKPLCHSED EKLSFEAVRN IHKLMDDDAN GDVDVEESDE FLREDLNYHD PTVKHSTFHG EDKLISVEDL WKAWKSSEVY NWTVDEVVQW LITYVELPQY EETFRKLQLS GHAMPRLAVT NTTMTGTVLK MTDRSHRQKL QLKALDTVLF GPPLLTRHNH LKD
Expression System E.coli
Grade & Purity > 90% pure
Molecular Weight 38 kDa (343 aa), confirmed by MALDI-TOF.
Tag/Conjugate Calmodulin tag
Form & Buffer Supplied as a liquid in 20mM Tris, pH 7.5.
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Stromal interaction molecule 1 (STIM1) is a transmembrane protein that is essential for store-operated Ca(2+) entry, a process of extracellular Ca(2+) influx in response to the depletion of Ca(2+) stores in the endoplasmic reticulum (ER). STIM1 localizes predominantly to the ER; upon Ca(2+) release from the ER, STIM1 translocates to the ER-plasma membrane junctions and activates Ca(2+) channels. Recombinant Calmodulin tagged STIM was expressed in E. coli and purified by using conventional chromatography techniques.

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Images

  • Coomassie Blue stained SDS-PAGE of STIM1 protein (Calmodulin tag) (80R-1062) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: €239.92
Size: 100 ug
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