SUMO3 protein (His tag) (80R-1512)
Purified recombinant Human SUMO3 protein
|Synonyms||SUMO 3 protein, SUMO-3 protein, SMT3A protein, SMT3H1 protein, SUMO 3, Small ubiquitin-related modifier 3 protein, SUMO-3, SUMO-3, SUMO3|
Coomassie Blue stained SDS-PAGE of SUMO3 protein (His tag) (80R-1512)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-92 amino acids: MGSSHHHHHH SSGLVPRGSH MSEEKPKEGV KTENDHINLK VAGQDGSVVQ FKIKRHTPLS KLMKAYCERQ GLSMRQIRFR FDGQPINETD TPAQLEMEDE DTIDVFQQQT GG|
|Grade & Purity||> 95% pure|
|Molecular Weight||12.6 kDa (112aa) confirmed by MALDI-TOF (molecular size on SDS-PAGE will appear higher)|
|Form & Buffer||0.1M NaClSupplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 20% glycerol, 0.1M NaCl and 1mM DTT.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||SUMO3, also known as small ubiquitin-related modifier 3, is a member of the SUMO protein family and functions in a manner similar to ubiquitin. However, unlike ubiquitin which targets proteins for degradation, SUMO3 protein participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It regulates amyloid beta generation and may be critical in the onset or progression of Alzheimer’s disease. Recombinant human SUMO3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.|
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