SYT11 protein (80R-4310)
Purified Recombinant SYT11 protein (His tagged)
Overview
Overview
| Synonyms | SYT12 protein, sytXI protein |
|---|---|
| Species | Human |
| Protein Type | Recombinant |
| Applications | SDS-PAGE |
Images
SDS-PAGE analysis using SYT11 protein (His tag) (80R-4310)
Figure annotation denotes ug of protein loaded and % gel used.
Specifications
| Residues | 37-431 aa: MGSSHHHHHH SSGLVPRGSH MGSWSCCHQQ AEKKQKNPPY KFIHMLKGIS IYPETLSNKK KIIKVRRDKD GPGREGGRRN LLVDAAEAGL LSRDKDPRGP SSGSCIDQLP IKMDYGEELR SPITSLTPGE SKTTSPSSPE EDVMLGSLTF SVDYNFPKKA LVVTIQEAHG LPVMDDQTQG SDPYIKMTIL PDKRHRVKTR VLRKTLDPVF DETFTFYGIP YSQLQDLVLH FLVLSFDRFS RDDVIGEVMV PLAGVDPSTG KVQLTRDIIK RNIQKCISRG ELQVSLSYQP VAQRMTVVVL KARHLPKMDI TGLSGNPYVK VNVYYGRKRI AKKKTHVKKC TLNPIFNESF IYDIPTDLLP DISIEFLVID FDRTTKNEVV GRLILGAHSV TASGAEHWRE VCESPRKPVA KWHSLSEY |
|---|---|
| Expression System | E.coli |
| Grade & Purity | > 80% pure |
| Molecular Weight | 47 kDa |
| Tag/Conjugate | His tag |
| Form & Buffer | Supplied in liquid form in PBS buffer (pH 7.4) containing 50% glycerol |
| Concentration | 250 ug/ml |
Storage & Safety
| Storage | Store at 4 deg C for short term storage. For long term storage, aliquot and store at -20 or -70 deg C. Avoid repeat freeze/thaw cycles |
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General Information
| Biological Significance | SYT11 also known as synaptotagmin-11. The protein may be involved in Ca2+-dependent exocytosis of secretory vesicles through Ca2+ and phospholipid binding to the C2 domain or may serve as Ca2+ sensors in the process of vesicular trafficking and exocytosis. A synaptotagmin potentially involved in Parkinson´s desease and schizophrenia. Recombinant human SYT11, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
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