TACI protein (30R-AT076)

Purified recombinant Human TACI protein

Synonyms TNFRSF13B protein, Transmembrane activator and CAML interactor protein
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of TACI protein corresponding to amino acids MSGLGRSRRG GRSRVDQEER FPQGLWTGVA MRSCPEEQYW DPLLGTCMSC KTICNHQSQR TCAAFCRSLS CRKEQGKFYD HLLRDCISCA SICGQHPKQC AYFCENKLRS PVNLPPELRR QRSGEVENNS DNSGRYQGLE HRGSEASPAL PGLKLSADQV.
Expression System E.coli
Grade & Purity > 98% pure
Molecular Weight 17.8 kDa
Form & Buffer Supplied as a lyophilized powder.

Usage & Assay Information

Bioactivity Determined by its ability to bl DEG Ck human BAFF induced T2B cell survival using a concentration range of 1.0-3.0 ug/ml.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance TACI, a member of the TNF Receptor superfamily, is expressed in the small intestine, spleen, thymus, peripheral blood leukocytes, activated T cells, and resting B cells. TACI binds to both APRIL and BAFF and can stimulate the activation of transcription factors; NF-kappaB, AP-1, and mediates calcineurin dependent activation of NF-AT (nuclear-factor of activated T cells). TACI also plays a key role in the stimulation of B and T cell function. Soluble TACI inhibits APRILstimulated proliferation of primary B-cells by blocking the binding of APRIL to the membrane anchored TACI receptor.

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Availability: In stock

Price: €211.69
Size: 20 ug
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