TAFI antibody (70R-10605)
Affinity purified sheep polyclonal TAFI antibody
Overview
Overview
| Synonyms | Polyclonal TAFI antibody, Anti-TAFI antibody, Carboxypeptidase B2 antibody, CPB2 antibody, PCPB antibody, CPU antibody |
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| Applications | User optimized |
| Immunogen | TAFI antibody was raised in sheep using human TAFI purified from plasma as the immunogen. |
Specifications
| Host | Sheep |
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| Isotype | IgG |
| Method of Purification | TAFI antibody was purified by affinity chromatography |
| Form & Buffer | Supplied in liquid form with 10 mM HEPES, pH 7.4, 150 mM NaCl, 50% (v/v) glycerol. |
Storage & Safety
| Storage | Store at -10 to -20 deg C. Product will become viscous but will not freeze. Avoid storage in frost-free freezers. Allow product to warm to room temperature and gently mix before use. |
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General Information
| Biological Significance | Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. |
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