ODD: 10 uL antiserum vs 3 uL Uromucoimmunodiffusion 50 mg/l, WB: 100 uL antiserum vs 5 uL Uromucoimmunodiffusion 50 mg/L, Immunodiffusion: 10 uL antiserum/cm^2 in gel vs 5 uL Uromucoimmunodiffusion (50 mh/L), dilutions: Neat - 1:5.
Storage & Safety
Storage
Store at 4 deg C.
Biohazard Information
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
General Information
Biological Significance
The Tamm-Horsfall glycoprotein (THP) also known as uromodulin is a glycoprotein that in humans is encoded by the UMOD gene. Uromodulin is the most abundant protein in normal urine. Uromodulin may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of uromodulin in urine may provide defense against urinary tract infections caused by uropathogenic bacteria.