Tamm-Horsfall Glycoprotein antibody (20C-CR2027SP)

Sheep polyclonal Tamm-Horsfall Glycoprotein antibody

Synonyms Polyclonal Tamm-Horsfall Glycoprotein antibody, Anti-Tamm-Horsfall Glycoprotein antibody, THG antibody
Specificity Human
Cross Reactivity To be determined by end-user
Applications Immunodiffusion, ODD, WB
Immunogen Tamm-Horsfall glycoprotein antibody was raised in sheep using human Tamm-Horsfall glycoprotein (Uromucoid) purified from urine as the immunogen.

Specifications

Host Sheep
Form & Buffer PBS, pH 7.4, with 0.05% NaN3.
Concentration Batch dependent - please inquire should you have specific requirements

Usage & Assay Information

Usage Recommendations ODD: 10 uL antiserum vs 3 uL Uromucoimmunodiffusion 50 mg/l, WB: 100 uL antiserum vs 5 uL Uromucoimmunodiffusion 50 mg/L, Immunodiffusion: 10 uL antiserum/cm^2 in gel vs 5 uL Uromucoimmunodiffusion (50 mh/L), dilutions: Neat - 1:5.

Storage & Safety

Storage Store at 4 deg C.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

General Information

Biological Significance The Tamm-Horsfall glycoprotein (THP) also known as uromodulin is a glycoprotein that in humans is encoded by the UMOD gene. Uromodulin is the most abundant protein in normal urine. Uromodulin may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of uromodulin in urine may provide defense against urinary tract infections caused by uropathogenic bacteria.

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Availability: In stock

Price: €348.87
Size: 1 ml
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