TANK protein (30R-1306)

Purified recombinant Human TANK protein

Synonyms TRAF interacting protein TANK isoform b protein, TRAF interacting protein protein, TRAF family member associated NFKB activator protein, TRAF2 protein, I-TRAF protein, TRAF interacting protein TANK isoform a, ITRAF protein, TRAF family member associated NF KAPPA B activator protein, TRAF interacting protein TANK isoform b I TRAF protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of TANK protein (30R-1306)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-119 amino acids: MDKNIGEQLN KAYEAFRQAC MDRDSAVKEL QQKTENYEQR IREQQEQLSL QQTIIDKLKS QLLLVNSTQD NNYGCVPLLE DSETRKNNLT LDQPQDKVIS GIAREKLPKV DIASAESSI
Expression System E.coli
Grade & Purity > 90% pure
Molecular Weight 13.6 kDa (119 aa), confirmed by MALDI-TOF.
Form & Buffer Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0.
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance TANK, also known as TRAF(tumor necrosis factor receptor-associated Factor)-interacting protein, is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby proposing that this protein is an inhibitor of TRAF function that regulates TRAF protein activity by sequestering TRAFs in a latent state in the cytoplasm. Overexpression of TANK inhibits TRAF2-mediated NF-Kappa-B activation signaled by CD40 and both TNF receptors and inhibits LMP1-mediated NF-kappa-B activation by blocking the association of TRAF2 with LMP1. Recombinant human TANK protein was expressed in E. coli and purified by using conventional chromatography techniques.

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Images

  • Coomassie Blue stained SDS-PAGE of TANK protein (30R-1306) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: €216.40
Size: 100 ug
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