Tau antibody (10R-T101a)

Mouse monoclonal Tau antibody

Synonyms Monoclonal Tau antibody, Anti-Tau antibody, Tau antibody, Anti Tau antibody, NFT antibody, PHF antibody, PHF antibody, NFT antibody
Specificity Bovine
Cross Reactivity Human, mouse, rat, sheep
Applications IF, IP, WB
Immunogen Tau antibody was raised in mouse using purified bovine microtubule-associated proteins as the immunogen.

Specifications

Host Mouse
Clone TAU-5
Isotype IgG1
Method of Purification Tau antibody was purified by Protein G chromatography.
Molecular Weight 45-68 kDa (predicted detection band MW)
Form & Buffer Antibody purified from ascites and supplied in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% NaN3.
Concentration 0.2 mg/ml

Usage & Assay Information

Usage Recommendations IP: 2ug/mg protein lysate, WB: 1-2 ug/ml

Storage & Safety

Storage Store at 4 deg C.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.

General Information

Biological Significance The neurofibrillary tangles (NFT) are neuronal inclusions that are the hallmark lesions of Alzheimer’s disease (AD). These tangles are made up of paired helical filaments (PHF). The PHF are highly insoluble structures and are known to be composed of a highly phosphorylated form of the microtubule-associated protein tau and may contain associated lipid.

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