Polyclonal TBCC antibody, Anti-TBCC antibody, tubulin-specific chaperone C antibody, CFC antibody, tubulin folding cofactor C antibody, TBCC antibody, tubulin-folding cofactor C antibody
Cross Reactivity
Human, Mouse
Applications
WB
Immunogen
TBCC antibody was raised in rabbit using a recombinant protein fragment contain a sequence corresponding to a region within amino acids 52 and 306 of TBCC
Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
General Information
Biological Significance
Cofactor C is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.