TFIID antibody (70R-12557)
Affinity purified Rabbit polyclonal TFIID antibody
Overview
Overview
| Synonyms | Polyclonal TFIID antibody, Anti-TFIID antibody, GTF2D antibody, MGC126054 antibody, TATA-box-binding protein antibody, TATA sequence-binding protein antibody, SCA17 antibody, transcription initiation factor TFIID TBP subunit antibody, TFIID antibody, TBP antibody, HDL4 antibody, TATA-box binding protein N-terminal domain antibody, TATA box binding protein antibody, TATA-box factor antibody, MGC126055 antibody, GTF2D1 antibody, MGC117320 antibody |
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| Cross Reactivity | Human |
| Applications | IHC-P, WB |
| Immunogen | TFIID antibody was raised in rabbit using a recombinant fragment corresponding to a region within amino acids 158 and 339 of TFIID |
Specifications
| Host | Rabbit |
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| Isotype | IgG |
| Method of Purification | TFIID antibody was purified by Protein A chromatography |
| Molecular Weight | 38 kDa |
| Form & Buffer | Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative. |
| Concentration | 7.36 mg/ml |
Usage & Assay Information
| Usage Recommendations | IHC-P: 1:100-1:500, WB: 1:500-1:3000 |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. |
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