TFRC protein (His tag) (80R-4118)
Recombinant Human TFRC protein (His tag)
Overview
Overview
| Synonyms | Transferrin receptor protein 1 protein, CD71 protein, p90 protein, T9 protein, TFR protein, TFR1 protein, TR protein, TRFR protein |
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| Species | Human |
| Protein Type | Recombinant |
| Applications | SDS-PAGE |
Images
SDS-PAGE analysis of TFRC protein (His tag) (80R-4118)
Figure annotated with amount of protein analysed and % SDS PAGE gel.
Specifications
| Residues | 89-760 amino acids: MGSSHHHHHH SSGLVPRGSH MGSMCKGVEP KTECERLAGT ESPVREEPGE DFPAARRLYW DDLKRKLSEK LDSTDFTGTI KLLNENSYVP REAGSQKDEN LALYVENQFR EFKLSKVWRD QHFVKIQVKD SAQNSVIIVD KNGRLVYLVE NPGGYVAYSK AATVTGKLVH ANFGTKKDFE DLYTPVNGSI VIVRAGKITF AEKVANAESL NAIGVLIYMD QTKFPIVNAE LSFFGHAHLG TGDPYTPGFP SFNHTQFPPS RSSGLPNIPV QTISRAAAEK LFGNMEGDCP SDWKTDSTCR MVTSESKNVK LTVSNVLKEI KILNIFGVIK GFVEPDHYVV VGAQRDAWGP GAAKSGVGTA LLLKLAQMFS DMVLKDGFQP SRSIIFASWS AGDFGSVGAT EWLEGYLSSL HLKAFTYINL DKAVLGTSNF KVSASPLLYT LIEKTMQNVK HPVTGQFLYQ DSNWASKVEK LTLDNAAFPF LAYSGIPAVS FCFCEDTDYP YLGTTMDTYK ELIERIPELN KVARAAAEVA GQFVIKLTHD VELNLDYERY NSQLLSFVRD LNQYRADIKE MGLSLQWLYS ARGDFFRATS RLTTDFGNAE KTDRFVMKKL NDRVMRVEYH FLSPYVSPKE SPFRHVFWGS GSHTLPALLE NLKLRKQNNG AFNETLFRNQ LALATWTIQG AANALSGDVW DIDNEF |
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| Expression System | E.coli |
| Grade & Purity | > 80% pure |
| Molecular Weight | 77.7 kDa |
| Tag/Conjugate | His tag |
| Form & Buffer | Supplied as liquid in 20mM Tris-HCl buffer, pH 8.0 containing 10% glycerol |
| Concentration | 1 mg/ml |
Storage & Safety
| Storage | Store at 4 deg C short term. Aliquot and store at -70 deg C for long term and avoid repeated freeze thaw cycles |
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General Information
| Biological Significance | TFRC also known as transferrin receptor protein 1. TFRC is required for iron delivery from transferring to cells. This protein is a transmembrane glycoprotein composed of two disulfide-linked monomers joined by two disulfide bonds. Each monomer binds one holo-transferrin molecule creating an iron-Tf-TfR complex which enters the cell by endocytosis. Recombinant human TFRC protein, fused to His-tag at N-terminus, was expressed in E.coli. |
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