TGF beta 1 protein (30R-1383)
Purified recombinant Human TGF beta 1 protein
|Synonyms||TGFB protein, DPD1 protein, CED protein, , Transforming growth factor beta 1 protein, Camurati-Engelmann disease protein, TGFbeta protein, TGFB1 protein|
Coomassie Blue stained SDS-PAGE of TGF beta 1 protein (30R-1383)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||279-390 amino acids: MALDTNYCFS STEKNCCVRQ LYIDFRKDLG WKWIHEPKGY HANFCLGPCP YIWSLDTQYS KVLALYNQHN PGASAAPCCV PQALEPLPIV YYVGRKPKVE QLSNMIVRSC KCS|
|Grade & Purity||> 95% pure|
|Molecular Weight||12.9 kDa (113aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in 10mM sodium citrate, pH 3.5, containing 10% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Endotoxin Levels||< 1.0 EU per ug of protein (determined by LAL method)|
|Biological Significance||Transforming growth factor beta 1 (TGF-beta1) is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. Many cells synthesize TGFb1 and almost all of them have specific receptors for it. It positively and negatively regulates many other growth factors. Also, TGF-beta1 plays an important role in bone remodeling, controlling the immune system, and shows different activities on different types of cell, or cells at different developmental stages. Recombinant TGF-beta1 protein was expressed in E. coli and purified by using conventional chromatography techniques.|
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