TGFB1 protein (His tag) (80R-4053)
Recombinant Mouse TGFB1 protein (His tag)
Overview
Overview
| Synonyms | Transforming growth factor beta-1 protein, TGF-beta1 protein, Tgfb protein, Tgfb-1 protein, TGFbeta1 protein |
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| Species | Mouse |
| Protein Type | Recombinant |
| Applications | SDS-PAGE |
Images
SDS-PAGE analysis of TGFB1 protein (His tag) (80R-4053)
Figure annotated with amount of protein analysed and % SDS PAGE gel.
Specifications
| Residues | 279-390 amino acids: MGSSHHHHHH SSGLVPRGSH MGSALDTNYC FSSTEKNCCV RQLYIDFRKD LGWKWIHEPK GYHANFCLGP CPYIWSLDTQ YSKVLALYNQ HNPGASASPC CVPQALEPLP IVYYVGRKPK VEQLSNMIVR SCKCS |
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| Expression System | E.coli |
| Grade & Purity | > 85% pure |
| Molecular Weight | 15 kDa |
| Tag/Conjugate | His tag |
| Form & Buffer | Supplied as liquid in 20mM Tris-HCl, pH 8.0 containing 10% glycerol. |
| Concentration | 250 ug/ml |
Storage & Safety
| Storage | Store at 4 deg C short term. Aliquot and store at -70 deg C for long term and avoid repeated freeze thaw cycles |
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General Information
| Biological Significance | Members of the Transforming growth factor beta (TGFB) family of cytokines are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. TGFB1 is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. Recombinant mouse TGFB1 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
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