Thrombomodulin protein (30R-3336)
Purified recombinant Thrombomodulin protein
Overview
Overview
| Synonyms | Thrombomodulin antigen, THRM protein, TM protein, TRBM protein, THBD protein, AHUS6 protein, CD141 protein, Fetomodulin protein |
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| Protein Type | Recombinant |
Specifications
| Expression System | HEK293 cells |
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| Grade & Purity | > 98% pure |
| Form & Buffer | Supplied in lyophilized form |
Usage & Assay Information
| Bioactivity | Measured by its ability to activate protein C induced cleavage of the chromogenic substrate, BOC-Asp-Pro Arg-AMC in the presence of thrombin. The specific activity is greater than 500 pmoles/min/ug. |
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Storage & Safety
| Storage | Store at -20 deg C |
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General Information
| Biological Significance | Thrombomodulin is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. |
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