Thrombomodulin protein (80R-4191)

Purified recombinant Thrombomodulin protein

Synonyms Thrombomodulin protein, AHUS6 protein, CD141 protein, CD141 antigen, Fetomodulin protein, THRM protein, TM protein, TRBM protein, THBD protein
Species Human
Protein Type Recombinant

Specifications

Residues Expression Region:19-515aa;
Expression System E.coli
Grade & Purity > 90% pure
Form & Buffer Supplied in a Tris-based buffer with 50% glycerol

Storage & Safety

Storage Store at -20 deg C, for extended storage, conserve at -20 deg Cor -80 deg C. Repeated freezing and thawing is not recommended. Store working aliquots at 4 deg Cfor up to one week.

General Information

Biological Significance Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated. Defects in THBD are the cause of thrombophilia due to thrombomodulin defect (THPH12).

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Availability: In stock

Price: €1,585.28
Size: 500 ug
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