Thyroglobulin ELISA kit (55R-2258)
ELISA kit for the detection of Thyroglobulin in the research laboratory
Overview
Overview
| Synonyms | TG ELISA kit, AITD3 ELISA kit, TGN ELISA kit |
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| Applications | ELISA |
| Assay Information | Sample Types : serum, plasma, tissue homogenates,Detect Range : 10 ng/ml-160 ng/ml,Sensitivity : 5 ng/ml,Assay Time : 1-5h,Sample Volume : 50-100ul, Detection Wavelengt : 450 nm |
Storage & Safety
| Storage | Store at 2-8 deg C |
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General Information
| Biological Significance | Thyroglobulin (hTG) is a multiple glycosylated, water soluble iodoprotein. The molecular weight of appox. 660,000 Da is shared by two identical subunits. Thyroglobulin is synthesized in the thyrocytes of the thyroid gland and secreted into the lumen of the thyroid follicles. Iodination of the proteins tyrosyl residues lead to the precursors of the thyroid hormones T3 and T4. Finally the free T3 and free T4 are liberated into circulation, together with small amounts of thyroglobulin. Like for T3 and T4, synthesis and secretion of thyroglobulin is controlled by TSH and TRH. Suppressive medication using the thyroid hormones also leads to lower thyroglobulin serum concentration. |
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