TIAF1 protein (His tag) (80R-2460)
Purified recombinant TIAF1 protein (His tag)
Overview
Overview
| Synonyms | TIAF 1 protein, TGFB1-induced anti-apoptotic factor 1 protein, TIAF-1 protein, SPR210 protein, TIAF-1, MAJN protein, TIAF1, TIAF 1 |
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| Species | Human |
| Protein Type | Recombinant |
| Applications | SDS-PAGE |
Specifications
| Residues | MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMSS PSSPFREQSF LCAAGDAGEE SRVQVLKNEV RRGSPVLLGW VEQAYADKCV CGPSAPPAPT PPSLSQRVMC NDLFKVNPFQ LQQFRADPST ASLLLCPGGL DHKLNLRGKA WG |
|---|---|
| Expression System | E.coli |
| Grade & Purity | > 85% pure |
| Molecular Weight | 16.6 kDa |
| Tag/Conjugate | His tag |
| Form & Buffer | Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol |
Storage & Safety
| Storage | Store at 4 deg C for short term storage, for long term, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freeze-thaw cycles. |
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General Information
| Biological Significance | TGFB1-induced anti-apoptotic factor 1, also known as TIAF1, inhibits the cytotoxic effects of TNF-alpha and overexpressed TNF receptor adapters TRADD, FADD, and RIPK1. This protein involved in TGF-beta1 inhibition of IkappaB-alpha expression and suppression of TNF-mediated IkappaB-alpha degradation. |
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