Flow Cytometric analysis using TLE2 antibody (10R-7208)
Flow Cytometric analysis of HEK293T cells transfected with either recombinant TLE2 protein (red) or empty vector (blue) stained using TLE2 antibody
TLE2 antibody
Flow Cytometric analysis using TLE2 antibody (10R-7208)
Flow Cytometric analysis of HEK293T cells transfected with either recombinant TLE2 protein (red) or empty vector (blue) stained using TLE2 antibody
Western Blot analysis using TLE2 antibody (10R-7208)
Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant TLE2 protein (Right) or empty vector (Left) detected with TLE2 antibody
Specifications
Host
Mouse
Clone
5A6
Isotype
IgG1
Method of Purification
TLE2 antibody was purified by affinity chromatography.
Form & Buffer
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
General Information
Biological Significance
TLE2 belongs to the WD repeat Groucho/TLE family. It contains 6 WD repeats. TLE2 is a transcriptional corepressor that binds to a number of transcription factors. It inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.