TLR4 antibody (70R-11717)

Rabbit polyclonal TLR4 antibody

Synonyms Polyclonal TLR4 antibody, anti-TLR4 antibody, Toll-like receptor 4 antibody, TOLL antibody, TLR-4, TLR 4 antibody, ARMD10 antibody, TLR-4 antibody, TLR 4, CD284 antibody, TLR4, hToll antibody
Cross Reactivity Human
Applications FC, WB
Immunogen TLR4 antibody was raised in Rabbit using recombinant human TLR4 as the immunogen.

Images

Western Blot analysis using TLR4 antibody (70R-11717)

Western blot analysis of TLR4 in transfected HRK293 cells.

Specifications

Host Rabbit
Isotype IgG
Method of Purification TLR4 antibody was purified by affinity chromatography
Form & Buffer Supplied in PBS buffer, pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal
Concentration 200 ug/ml

Usage & Assay Information

Usage Recommendations WB: 0.5-4 ug/ml

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance TLR4 is a mammalain homologue of the Drosophila toll protein. The human TLR4 is a type-1 transmembrane protein containing 799 amino acid residues. The extracellular domain has leucine-rich repeats and the intracellular domain is similar to that of IL-1 receptor. TLR4 is a receptor for lipopolysaccharide. In mice that are genetically tolerant to endotoxin, mutations have been identified in the intracellular domain of TLR4 that abolish LPS responsiveness. TLR4 uses a mechanism similar to that of the IL-1 receptor for signal transduction that leads to activation of NF-kB.

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Images

  • <div><font face=Calibri size=2>Western Blot analysis using TLR4 antibody (70R-11717)</font></div>     | Western blot analysis of TLR4 in transfected HRK293 cells.

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Price: €303.48
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