TLR4 antibody (70R-14023)

Affinity purified Rabbit polyclonal TLR4 antibody

Synonyms Polyclonal TLR4 antibody, Anti-TLR4 antibody, TLR 4 antibody, hToll antibody, toll-like receptor 4 antibody, TLR4, TLR-4, ARMD10 antibody, TLR-4 antibody, TOLL antibody, CD284 antibody, TLR 4
Applications IHC-P, WB
Immunogen TLR4 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the N-terminal of human TLR4 as the immunogen

Images

Immunohistochemical staining using TLR4 antibody (70R-14023)

Immunohistochemistry of paraffin-embedded section of Human Lung Cancer Tissue

Specifications

Host Rabbit
Isotype IgG
Method of Purification TLR4 antibody was purified by affinity chromatography
Form & Buffer Supplied in lyophilized form

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles.

General Information

Biological Significance The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes. It has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Also, several transcript variants of this gene have been found, but the protein coding potential of most of them is uncertain.

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Images

  • <div><font face=Calibri size=2>Immunohistochemical staining using TLR4 antibody (70R-14023)</font></div>     | Immunohistochemistry of paraffin-embedded section of Human Lung Cancer Tissue
  • <div><font face=Calibri size=2>Western Blot analysis using TLR4 antibody (70R-14023)</font></div>     | Lane 1: Hela Cell Lysate; Lane 2: SMMC Cell Lysate

Availability: In stock

Price: €208.59
Size: 100 ug
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